Perioperative Best Practices and Delirium in Patients With Cognitive Impairment
This cohort study of surgical patients with cognitive impairment found that current perioperative strategies derived from established recommendations, while foundational, were insufficient to prevent postoperative delirium. The high rate of postoperative delirium highlights the need to refine perioperative care pathways and identify novel strategies that are most effective for cognitively vulnerable populations. Tailored interventions that integrate electronic health record-derived perioperative data and scalable technological tools in anesthesia workflows can help identify and manage high-risk populations.
Authors
- Alex D. Federman (ORCID: https://orcid.org/0000-0002-4824-064X)
- Catherine A. Sarkisian (ORCID: https://orcid.org/0000-0003-2768-2323)
- Girish N. Nadkarni (ORCID: https://orcid.org/0000-0001-6319-4314)
- Danielle Scharp (ORCID: https://orcid.org/0000-0002-3265-6667)
- Ira S. Hofer (ORCID: https://orcid.org/0000-0001-7456-6697)
- Matthew A. Levin (ORCID: https://orcid.org/0000-0002-6013-2684)
- Pooja Anand Gownivaripally (ORCID: https://orcid.org/0009-0004-1945-1861)
- Y. Ouyang
- N Egorova
- Kerry Meyers
- Spencer Perry
- Susana Vacas
Institutions
- West Los Angeles College (US)
- Los Angeles County Department of Health Services (US)
- University of California, Los Angeles (US)
- Massachusetts General Hospital (US)
- VA Greater Los Angeles Healthcare System (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1001/jamanetworkopen.2026.1515
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00