Functional insights into the biosynthesis of antifungal mandimycin
This study identifies mandimycin as a potential agricultural antifungal agent. The validation of the snt cluster reveals the key role of C-35 glycosylation in limiting production, offering a pathway for targeted metabolic engineering to enhance yield and improve sustainable crop protection. © 2026 Society of Chemical Industry.
Authors
- C. X. Zhang
- Fengying Shen
- Lei Li (ORCID: https://orcid.org/0000-0001-8723-3461)
- Xing Han (ORCID: https://orcid.org/0000-0002-3463-0292)
- Bocong Zhang
- Yue Zhang
- Yuan Cheng
- Xin Jia
Institutions
- Hebei North University (CN)
- Hebei University of Science and Technology (CN)
- Center for Agricultural Resources Research (CN)
Publication Details
- Journal
- Pest Management Science
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1002/ps.70717
- Primary Topic
- Microbial Natural Products and Biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00