CT-Based Assessment of Brain Edema May Predict Which Patients with Traumatic Brain Injury May Benefit from Tranexamic Acid
A voxel percentage of ≥3% within the 10-20 HU CT density range serves as a promising imaging biomarker associated with a survival benefit from TXA in patients with acute TBI in the prehospital setting. Prospective validation is required to confirm these findings before integrating this biomarker into clinical decision-making for personalized TBI management.
Authors
- Samir A. Dagher (ORCID: https://orcid.org/0000-0003-0155-7444)
- H.E. Hinson
- Martin Schreiber
- Prashant Raghavan
- Guangming Zhu
- Susan Rowell
- Max Wintermark
- Peter Kamel
- Maguy Farhat
Institutions
- University of Maryland, Baltimore (US)
- University of Maryland Medical Center (US)
- The University of Texas MD Anderson Cancer Center (US)
- University of Arizona (US)
- Uniformed Services University of the Health Sciences (US)
- University of California, San Francisco (US)
- University of Chicago Medical Center (US)
Publication Details
- Journal
- American Journal of Neuroradiology
- Published
- 2026-03-12
- DOI
- https://doi.org/10.3174/ajnr.a9174
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 0.00