Original research: Amplification of genetic and metabolic factors in alpha-1 antitrypsin deficiency
Our data demonstrate the interaction between genetic and metabolic risk factors in AATD and provide evidence for patient management.
Authors
- Katharina Remih (ORCID: https://orcid.org/0000-0001-9372-5761)
- Mattias Mandorfer (ORCID: https://orcid.org/0000-0003-2330-0017)
- Katrine Holtz Thorhauge (ORCID: https://orcid.org/0000-0003-0411-0373)
- N G Mcelvaney
- Guido Stirnimann (ORCID: https://orcid.org/0000-0003-3447-264X)
- B. van Hoek
- Malin Fromme (ORCID: https://orcid.org/0000-0003-0382-5705)
- Jan Stolk
- Audrey Payancé (ORCID: https://orcid.org/0000-0001-7978-7982)
- Zoe Mariñó (ORCID: https://orcid.org/0000-0001-6321-9534)
- Jef Verbeek (ORCID: https://orcid.org/0000-0002-1549-8003)
- Virginia Clark (ORCID: https://orcid.org/0000-0001-6719-3634)
- J Genesca
- Annelot D. Sark
- Christina Schrader (ORCID: https://orcid.org/0009-0004-9736-3250)
- Marc Miravitlles (ORCID: https://orcid.org/0000-0002-9850-9520)
- Jan Šperl (ORCID: https://orcid.org/0000-0001-8619-2610)
- Andreas Emanuel Kremer (ORCID: https://orcid.org/0000-0002-9263-948X)
- P Strnad
- Benedikt Schaefer (ORCID: https://orcid.org/0000-0001-8690-2774)
- E Weber
- A. W. Turner
- W.J.H. Griffiths
- H Bantel
- Joanna Chorostowska-Wynimko
- Monica Pons
- Heinz Zoller
- Sophie Gensluckner
- Michael Trauner
- Sona Frankova
- Rohit Loomba
- Paul Ellis
- Lorenz Balcar
- Elmar Aigner
- Aleksander Krag
Institutions
- University of Bern (CH)
- Royal College of Surgeons in Ireland (IE)
- Innsbruck Medical University (AT)
- University of Southern Denmark (DK)
- University of Zurich (CH)
- Université Paris Cité (FR)
- Paracelsus Medical University (AT)
- Hôpital Beaujon (FR)
- Leiden University Medical Center (NL)
- University Hospital of Bern (CH)
- Instituto de Salud Carlos III (ES)
- Odense University Hospital (DK)
- Beaumont Hospital (IE)
- Cambridge University Hospitals NHS Foundation Trust (GB)
- University of Florida (US)
- Medizinische Hochschule Hannover (DE)
- University of California San Diego (US)
- Assistance Publique – Hôpitaux de Paris (FR)
- University Hospital of Zurich (CH)
- Vall d'Hebron Institut de Recerca (ES)
- Vall d'Hebron Hospital Universitari (ES)
- Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (ES)
- ERN GUARD-Heart (NL)
- Medizinische Universität Lausitz - Carl Thiem (DE)
- Medical University of Vienna (AT)
- University of Birmingham (GB)
- RWTH Aachen University (DE)
Publication Details
- Journal
- Hepatology
- Published
- 2026-03-11
- DOI
- https://doi.org/10.1097/hep.0000000000001710
- Primary Topic
- Protease and Inhibitor Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00