Biological age acceleration in primary aldosteronism: associations with renin, aldosterone, aldosterone-to-renin ratio, and left ventricular mass index

Among patients with primary aldosteronism, elevated ARR and PAC were independently associated with GOLD BioAgeDiff, and GOLD BioAgeDiff was correlated with LVMI/eLVMI and may be involved in the association between ARR and eLVMI. Prospective studies are required to confirm causality and evaluate the clinical utility of this biological aging marker.

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Publication Details

Journal
Journal of Hypertension
Published
2026-03-12
DOI
https://doi.org/10.1097/hjh.0000000000004295
Primary Topic
Hormonal Regulation and Hypertension
Type
article
Field-Weighted Citation Impact
0.00
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article

Biological age acceleration in primary aldosteronism: associations with renin, aldosterone, aldosterone-to-renin ratio, and left ventricular mass index

Yifei Dong, Ning Li, Ningpeng Liang, Xiangtao Zhang
Journal of Hypertension
Hormonal Regulation and Hypertension
article

Biological age acceleration in primary aldosteronism: associations with renin, aldosterone, aldosterone-to-renin ratio, and left ventricular mass index

Yifei Dong, Ning Li, Ningpeng Liang, Xiangtao Zhang
article en

Abstract

Among patients with primary aldosteronism, elevated ARR and PAC were independently associated with GOLD BioAgeDiff, and GOLD BioAgeDiff was correlated with LVMI/eLVMI and may be involved in the association between ARR and eLVMI. Prospective studies are required to confirm causality and evaluate the clinical utility of this biological aging marker.

Journal of Hypertension
Nanchang University (CN), First Affiliated Hospital of Jiangxi Medical College (CN), Second Affiliated Hospital of Nanchang University (CN)
Openalex Percentile: Top 25%
Hormonal Regulation and Hypertension
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