Development of a predictive model based on aqueous cytokines data for response to anti-VEGF therapy in diabetic macular edema

The baseline cytokine-based model helped to assess the individual probability of response to anti-VEGF therapy. There are cytokines beyond VEGF that are involved in the pathogenesis of DME, therapeutic regimens targeting these cytokines may improve the visual acuity and reduce macular edema.

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Publication Details

Journal
Eye and Vision
Published
2026-03-13
DOI
https://doi.org/10.1186/s40662-026-00479-z
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Development of a predictive model based on aqueous cytokines data for response to anti-VEGF therapy in diabetic macular edema

Liangzhang Tan, Rongguo Yu, Xiaoying Pan, Fuhua Yang et al.
Eye and Vision
Retinal Diseases and Treatments
article

Development of a predictive model based on aqueous cytokines data for response to anti-VEGF therapy in diabetic macular edema

Liangzhang Tan, Rongguo Yu, Xiaoying Pan, Fuhua Yang, Xiaomin Zhang, Jinzhi Zhao, Yi Gong, Xiaorong Li, Emmanuel Eric Pazo
article en

Abstract

The baseline cytokine-based model helped to assess the individual probability of response to anti-VEGF therapy. There are cytokines beyond VEGF that are involved in the pathogenesis of DME, therapeutic regimens targeting these cytokines may improve the visual acuity and reduce macular edema.

Eye and VisionVol. 13(1)
Tianjin Medical University Eye Hospital (CN), Tianjin Medical University (CN)
Tianjin Medical University, Tianjin Medical University Eye Hospital
No poverty
Openalex Percentile: Top 24%
Retinal Diseases and Treatments
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