Soluble endoglin as a biomarker of cardiovascular and metabolic disorders related to endothelial dysfunction: a systematic review and meta-analysis
This meta-analysis is the first to demonstrate that sENG serum/plasma concentrations are significantly higher in selected cardiovascular and metabolic disorders related to endothelial dysfunction. sENG might represent a novel biomarker reflecting endothelial damage only in patients with DM1, DM2, and heart failure.
Authors
- Ivana Němečková (ORCID: https://orcid.org/0000-0002-9795-8471)
- K. Tripská (ORCID: https://orcid.org/0000-0001-6722-8614)
- Jana Rathouska (ORCID: https://orcid.org/0000-0001-6363-9715)
- Petra Fikrová (ORCID: https://orcid.org/0000-0003-0484-6049)
- Petr Nachtigal (ORCID: https://orcid.org/0000-0001-9568-7295)
- Tannaz Jamialahmadi
- Niloufar Mohammadi
- Maryam Emadzadeh
- Amirhossein Sahebkar
Institutions
- Mashhad University of Medical Sciences (IR)
- Charles University (CZ)
- University Hospital Hradec Králové (CZ)
- Ghaem Hospital (IR)
- University of Hradec Králové (CZ)
Publication Details
- Journal
- Atherosclerosis
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1016/j.atherosclerosis.2026.120704
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Grantová Agentura České Republiky