Association Between Severe Aortic Stenosis and Amyloid Deposition in the Myocardium of Patients With Wild-Type Transthyretin Cardiac Amyloidosis

Background: Although wild-type transthyretin cardiac amyloidosis (ATTRwt-CA) is frequently observed in older patients with aortic stenosis (AS), its relationship with AS is unclear. Therefore, this exploratory study aimed to investigate the relationship between myocardial amyloid deposition and AS in patients with ATTRwt-CA.

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Publication Details

Journal
Circulation Reports
Published
2026-03-12
DOI
https://doi.org/10.1253/circrep.cr-26-0014
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
Field-Weighted Citation Impact
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Association Between Severe Aortic Stenosis and Amyloid Deposition in the Myocardium of Patients With Wild-Type Transthyretin Cardiac Amyloidosis

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Association Between Severe Aortic Stenosis and Amyloid Deposition in the Myocardium of Patients With Wild-Type Transthyretin Cardiac Amyloidosis

Kentaro Furukawa, Tsuyoshi Yoshimuta, Chisa Eguchi, Yusuke Takenaka, Tomohiro Honda, Masamichi Eguchi, Ryohei Akashi, S Ikeda, Hiroaki Kawano, Koji Maemura, Takashi Kudo, Mitsuharu Ueda, Masahiro Nakashima, Tadatomo Fukushima
article en

Abstract

Background: Although wild-type transthyretin cardiac amyloidosis (ATTRwt-CA) is frequently observed in older patients with aortic stenosis (AS), its relationship with AS is unclear. Therefore, this exploratory study aimed to investigate the relationship between myocardial amyloid deposition and AS in patients with ATTRwt-CA.

Circulation Reports
Nagasaki University Hospital (JP), Nagasaki University (JP), Kumamoto University (JP)
Zero hunger
Openalex Percentile: Top 24%
Amyloidosis: Diagnosis, Treatment, Outcomes
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