The Human Organ Atlas

We present the Human Organ Atlas (HOA), an open data repository making accessible multiscale three-dimensional imaging of human organs. The repository also provides software tools and training resources enabling worldwide access, sharing, and analysis of these datasets, facilitating further research and the continued expansion of the HOA. The images are generated using a synchrotron imaging technique, hierarchical phase-contrast tomography (HiP-CT), that uses the ESRF's Extremely Brilliant Source, spanning whole-organ imaging at ~20 micrometers/voxel with local volumes of interest within intact organs imaged down to ~1 micrometer/voxel. This offers a comprehensive exploration of human anatomy, providing unparalleled insights into intricate structures and spatial relationships. The HOA offers researchers, clinicians, and educators a valuable resource for anatomical study, image analysis, medical education, and large-scale data mining.

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Publication Details

Journal
Science Advances
Published
2026-03-11
DOI
https://doi.org/10.1126/sciadv.adz2240
Primary Topic
Advanced X-ray Imaging Techniques
Type
article
Field-Weighted Citation Impact
0.00
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article

The Human Organ Atlas

Theresa Urban, Joseph Jacob, Anna Maria, Axel Bocciarelli et al.
Science Advances
Advanced X-ray Imaging Techniques
article

The Human Organ Atlas

Theresa Urban, Joseph Jacob, Anna Maria, Axel Bocciarelli, Marjolaine Bodin, Stijn E. Verleden, Claire Walsh, Alexandre Bellier, Joanna Purzycka, Camille Berruyer, M. Ackermann, Ruikang Xue, Guillaume Gaisné, Joseph Brunet, B. de Bakker, Peter D. Lee, Yang Zhou, Andy Götz, David Stansby, Paul Tafforeau, Hector Dejea, Daniel Jonigk, Klaus Engel
article en

Abstract

We present the Human Organ Atlas (HOA), an open data repository making accessible multiscale three-dimensional imaging of human organs. The repository also provides software tools and training resources enabling worldwide access, sharing, and analysis of these datasets, facilitating further research and the continued expansion of the HOA. The images are generated using a synchrotron imaging technique, hierarchical phase-contrast tomography (HiP-CT), that uses the ESRF's Extremely Brilliant Source, spanning whole-organ imaging at ~20 micrometers/voxel with local volumes of interest within intact organs imaged down to ~1 micrometer/voxel. This offers a comprehensive exploration of human anatomy, providing unparalleled insights into intricate structures and spatial relationships. The HOA offers researchers, clinicians, and educators a valuable resource for anatomical study, image analysis, medical education, and large-scale data mining.

Science AdvancesVol. 12(11)
Siemens (Germany) (DE), University of Antwerp (BE), Inserm (FR), Johannes Gutenberg University Mainz (DE), European Synchrotron Radiation Facility (FR), University Medical Center of the Johannes Gutenberg University Mainz (DE), German Center for Lung Research (DE), Systems, Applications & Products in Data Processing (United Kingdom) (GB), Siemens Healthineers (Germany) (DE), University College London (GB), University of Amsterdam (NL), RWTH Aachen University (DE), Université Grenoble Alpes (FR)
Openalex Percentile: Top 21%
Advanced X-ray Imaging Techniques
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