The genomic history of Streptococcus mutans from the Mesolithic until modern times
Our study demonstrates that Streptococcus mutans DNA is well preserved in tooth samples from archaeological remains and show that it formed part of the human oral microbiota already before the onset of agriculture, consistent with a radiation and population expansion well before 8,000 years ago.
Authors
- Jacqueline Abranches (ORCID: https://orcid.org/0000-0002-6615-7348)
- Martin Sikora (ORCID: https://orcid.org/0000-0003-2818-8319)
- Ghader Ebrahimi
- Daniel Belstrøm (ORCID: https://orcid.org/0000-0001-7116-5388)
- Gabriele Scorrano (ORCID: https://orcid.org/0000-0002-0887-4023)
- Florentin Constancias (ORCID: https://orcid.org/0000-0002-8612-384X)
- Motahare Feizabadi Farahani
- Sofie Nielsen (ORCID: https://orcid.org/0000-0001-7463-360X)
- Julio C. Bendezu-Sarmiento
- Fabrice Demeter
- Kristian Kristiansen
- Michael Givskov
- Marie Louise S. Jørkov
- Vincent F. D. F. Thygesen
Institutions
- Statens Serum Institut (DK)
- University of Rome Tor Vergata (IT)
- University of Copenhagen (DK)
- Centre National de la Recherche Scientifique (FR)
- Stockholm University (SE)
- Université Paris Cité (FR)
- University of Florida (US)
- Éco-Anthropologie (FR)
- University of Mohaghegh Ardabili (IR)
Publication Details
- Journal
- Genome biology
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1186/s13059-026-04018-w
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00