Single-cell Analysis of Human Kidney Biopsy Tissue Reveals Epithelial and Immune Cell Responses to BK Polyomavirus Infection
These not previously reported insights into BKV-associated injury may have implications for clinical management and improved allograft outcomes.
Authors
- Chandra L. Theesfeld
- Rachel Sealfon (ORCID: https://orcid.org/0000-0002-3007-4698)
- Céline C. Berthier (ORCID: https://orcid.org/0000-0003-3539-1075)
- Lalita Subramanian (ORCID: https://orcid.org/0000-0003-3424-8381)
- Olga G. Troyanskaya (ORCID: https://orcid.org/0000-0002-5676-5737)
- Fadhl Alakwaa (ORCID: https://orcid.org/0000-0001-5349-7960)
- Phillip J. McCown (ORCID: https://orcid.org/0000-0002-8012-1931)
- Abhijit Naik
- James M. Pipas (ORCID: https://orcid.org/0000-0003-1253-300X)
- Kelly Shaffer (ORCID: https://orcid.org/0000-0002-3134-459X)
- Michael J. Imperiale (ORCID: https://orcid.org/0000-0003-1218-6458)
- Silas P. Norman (ORCID: https://orcid.org/0000-0001-9779-6532)
- Edgar A. Otto (ORCID: https://orcid.org/0000-0002-2387-9973)
- Ramnika I. Gumber (ORCID: https://orcid.org/0000-0001-6313-1647)
- Rajasree Menon (ORCID: https://orcid.org/0000-0001-6280-9639)
- Tavis J. Reed (ORCID: https://orcid.org/0000-0002-0945-5461)
- Ping An (ORCID: https://orcid.org/0000-0002-3080-2288)
- Evan A. Farkash (ORCID: https://orcid.org/0000-0002-5136-079X)
- Paula Arrowsmith
- Tess A. Marvin
- Felix Eichinger (ORCID: https://orcid.org/0009-0001-1442-7617)
- Matthias Kretzler
Institutions
- University of Pittsburgh (US)
- Princeton University (US)
- University of Michigan (US)
- Ann Arbor Center for Independent Living (US)
- Flatiron Health (United States) (US)
Publication Details
- Journal
- JCI Insight
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1172/jci.insight.198227
- Primary Topic
- Polyomavirus and related diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00