Thrombin Generation in Pediatric Haemophilia A Patients on Extended Half‐Life FVIII versus Non‐FVIII Therapies
Pediatric patients on EHL-FVIII prophylaxis demonstrated higher ETP in vitro using PPP compared to those on EMI prophylaxis. These findings highlight the need for further systematic investigations to explore the implications of these differences in bleed control.
Authors
- Jéssica Garcia (ORCID: https://orcid.org/0000-0003-2627-5531)
- Sean G. Yates (ORCID: https://orcid.org/0000-0001-9703-5047)
- Ravi Sarode
- Guy Young
- Ayesha Zia
Institutions
- Children's Hospital of Los Angeles (US)
- Southwestern Medical Center (US)
- Southwestern Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Haemophilia
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1111/hae.70258
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00