Fast-acting approaches for treatment-resistant depression: real-world comparative effectiveness of Intranasal Esketamine versus accelerated rTMS
aTMS showed a stronger early antidepressant effect, but its advantage over esketamine progressively diminished and was no longer evident at six months. Prospective, well-powered comparative trials are required to validate these findings.
Authors
- Barbara Barbini (ORCID: https://orcid.org/0000-0002-4250-9062)
- Filippo Frizzi (ORCID: https://orcid.org/0000-0002-1419-0445)
- Greta Verri
- Mattia Tondello
- M. Prato
- Zanardi Raffaella
- Cristina Colombo
- Matteo Carminati
Institutions
- Vita-Salute San Raffaele University (IT)
- IRCCS Ospedale San Raffaele (IT)
Publication Details
- Journal
- International Journal of Psychiatry in Clinical Practice
- Published
- 2026-03-11
- DOI
- https://doi.org/10.1080/13651501.2026.2642680
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 0.00