Ifosfamide-Induced Encephalopathy in a Very Young Child With Rhabdomyosarcoma: Case Report and Literature Review
IIE is a rare but severe side effect of ifosfamide infusion, and clinical manifestations in children may be misunderstood. We speculate that pharmacogenetic testing may be warranted in very young children to prevent severe IIE.
Authors
- Mariachiara Servedio
- Francesco De Leonardis (ORCID: https://orcid.org/0000-0002-6278-1565)
- Chiara Novielli
- Enza Pentassuglia (ORCID: https://orcid.org/0009-0008-0372-3868)
- Roberta Koronica
- Nicola Santoro
Institutions
- Radiation Oncology Institute (US)
Publication Details
- Journal
- Journal of Pediatric Hematology/Oncology
- Published
- 2026-03-11
- DOI
- https://doi.org/10.1097/mph.0000000000003183
- Primary Topic
- Chemotherapy-induced organ toxicity mitigation
- Type
- article
- Field-Weighted Citation Impact
- 0.00