Giant placental chorioangioma and intrapartum acute fetal distress: A case report

Placental chorioangioma represents the most frequent benign non-trophoblastic tumor of the placenta. Most lesions are small and clinically silent, but giant chorioangiomas (4-5 cm), while uncommon, can be associated with serious complications. This report describes the case of a 27-year-old woman (gravida 2, para 1) with an uneventful pregnancy until 33 weeks, when an ultrasound identified a placental mass measuring 60 × 70 mm. At 36 weeks, she presented with spontaneous rupture of membranes and labor pains. During labor, the fetus developed acute distress, and an emergency cesarean section was performed. A female infant weighing 2360 g was delivered with Apgar scores of 7 and 9 at 1 and 5 min. Intraoperatively, a well-circumscribed placental tumor measuring 10 × 10 cm was observed. Histopathological analysis confirmed chorioangioma. Both mother and newborn were discharged in good health on postoperative day 5. Although often silent during pregnancy, giant placental chorioangiomas may precipitate acute intrapartum complications. Vigilant antenatal monitoring and timely intervention are crucial to optimize perinatal outcomes.

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Publication Details

Journal
Case Reports in Women s Health
Published
2026-03-11
DOI
https://doi.org/10.1016/j.crwh.2026.e00799
Primary Topic
Gestational Trophoblastic Disease Studies
Type
article
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article

Giant placental chorioangioma and intrapartum acute fetal distress: A case report

Hoa Trung Dinh, Tien Viet Tran, Hung Nguyen Dao, Son Tien Nguyen et al.
Case Reports in Women s Health
Gestational Trophoblastic Disease Studies
article

Giant placental chorioangioma and intrapartum acute fetal distress: A case report

Hoa Trung Dinh, Tien Viet Tran, Hung Nguyen Dao, Son Tien Nguyen, Kien Trung Nguyen, TUAN DINH LE, Nui Minh Nguyen, Trung Viet Nguyen, T. L. Quyen Bui, Hieu Trung Mai, Binh Van Nguyen
article en

Abstract

Placental chorioangioma represents the most frequent benign non-trophoblastic tumor of the placenta. Most lesions are small and clinically silent, but giant chorioangiomas (4-5 cm), while uncommon, can be associated with serious complications. This report describes the case of a 27-year-old woman (gravida 2, para 1) with an uneventful pregnancy until 33 weeks, when an ultrasound identified a placental mass measuring 60 × 70 mm. At 36 weeks, she presented with spontaneous rupture of membranes and labor pains. During labor, the fetus developed acute distress, and an emergency cesarean section was performed. A female infant weighing 2360 g was delivered with Apgar scores of 7 and 9 at 1 and 5 min. Intraoperatively, a well-circumscribed placental tumor measuring 10 × 10 cm was observed. Histopathological analysis confirmed chorioangioma. Both mother and newborn were discharged in good health on postoperative day 5. Although often silent during pregnancy, giant placental chorioangiomas may precipitate acute intrapartum complications. Vigilant antenatal monitoring and timely intervention are crucial to optimize perinatal outcomes.

Case Reports in Women s HealthVol. 50
Hung Yen University of Technology and Education (VN), Vietnam Military Medical University (VN), Vietnam National Children's Hospital (VN), Thai Binh University of Medicine and Pharmacy (VN), University College London (GB)
Openalex Percentile: Top 29%
Gestational Trophoblastic Disease Studies
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