Personalization of the implantation window and correction of the uterine microflora in a patient with repeated implantation failures

Repeated implantation failures (RIF) pose a serious problem in assisted reproductive technology (ART) programs, reducing their effectiveness. The diagnosis and treatment of RIF continue to generate active debate among specialists, with particular attention paid to the role of endometrial factors, including the state of the uterine microflora and endometrial receptivity. This article presents a clinical case of correction of uterine microflora composition and personalized embryo transfer in a patient with RIF during ART.

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Publication Details

Journal
Russian Bulletin of Obstetrician-Gynecologist
Published
2026-03-11
DOI
https://doi.org/10.17116/rosakush20262601171
Primary Topic
Reproductive System and Pregnancy
Type
article
Field-Weighted Citation Impact
0.00
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article

Personalization of the implantation window and correction of the uterine microflora in a patient with repeated implantation failures

N.L. Shamugiya, N.M. Podzolkova Podzolkova, P.M. Varlakova
Russian Bulletin of Obstetrician-Gynecologist
Reproductive System and Pregnancy
article

Personalization of the implantation window and correction of the uterine microflora in a patient with repeated implantation failures

N.L. Shamugiya, N.M. Podzolkova Podzolkova, P.M. Varlakova
article en

Abstract

Repeated implantation failures (RIF) pose a serious problem in assisted reproductive technology (ART) programs, reducing their effectiveness. The diagnosis and treatment of RIF continue to generate active debate among specialists, with particular attention paid to the role of endometrial factors, including the state of the uterine microflora and endometrial receptivity. This article presents a clinical case of correction of uterine microflora composition and personalized embryo transfer in a patient with RIF during ART.

Russian Bulletin of Obstetrician-GynecologistVol. 26(1)
Russian Medical Academy of Continuous Professional Education (RU), Botkin Hospital (RU), Boston IVF (US)
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Openalex Percentile: Top 24%
Reproductive System and Pregnancy
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