Development of mass spectrometry‐based genotyping method for simultaneous detection of 35 <scp>HPA</scp> systems, 5 <scp>HNA</scp> systems and the <scp>CD36</scp> antigen
We successfully developed an MS panel capable of detecting all currently known HPAs, HNAs, and the CD36 antigen, overcoming limitations of previous methods related to non-specific HNA-1 amplification. This method also demonstrated its efficacy in establishing a large-scale platelet donor database, and rare allele data support precise transfusion matching for special patients.
Authors
- Ruishu Li
- L. Ye
- Min Fu (ORCID: https://orcid.org/0000-0003-1413-3325)
- Qixiu Yang
- Qinqin Ma
- Ping Lu
- Ziyan Zhu
- Huijun Zhu
Institutions
- Shanghai Blood Center (CN)
Publication Details
- Journal
- Transfusion
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1111/trf.70167
- Primary Topic
- Blood disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00