Preoperative sarcopenia and its impact on postoperative complications in laparoscopic anti-reflux surgery: a clinical analysis

​Our findings clearly indicate that while preoperative sarcopenia does not elevate the risk of postoperative dysphagia, it significantly delays the recovery of gastrointestinal function and leads to lower albumin levels following surgery in gastroesophageal reflux disease patients. This underscores the critical clinical importance of recognizing sarcopenia as a modifiable preoperative risk factor. We therefore propose the integration of routine sarcopenia screening into the preoperative assessment for gastroesophageal reflux disease patients. For those diagnosed with sarcopenia, a targeted prehabilitation protocol emphasizing nutritional support and physical training could be implemented to potentially enhance surgical tolerance and recovery outcomes. Future studies are warranted to validate the efficacy of such prehabilitation strategies and to further investigate the precise molecular mechanisms through which sarcopenia impedes postoperative recovery.

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Publication Details

Journal
Frontiers in Surgery
Published
2026-03-11
DOI
https://doi.org/10.3389/fsurg.2026.1723324
Primary Topic
Gastroesophageal reflux and treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Preoperative sarcopenia and its impact on postoperative complications in laparoscopic anti-reflux surgery: a clinical analysis

F R Wang, Zhongyu Wang, Yuanyuan Wang, Ming Wei et al.
Frontiers in Surgery
Gastroesophageal reflux and treatments
article

Preoperative sarcopenia and its impact on postoperative complications in laparoscopic anti-reflux surgery: a clinical analysis

F R Wang, Zhongyu Wang, Yuanyuan Wang, Ming Wei, Jie Lin, Hong-Fei Pang, Yu-Hang Liu, Yu Liu
article en

Abstract

​Our findings clearly indicate that while preoperative sarcopenia does not elevate the risk of postoperative dysphagia, it significantly delays the recovery of gastrointestinal function and leads to lower albumin levels following surgery in gastroesophageal reflux disease patients. This underscores the critical clinical importance of recognizing sarcopenia as a modifiable preoperative risk factor. We therefore propose the integration of routine sarcopenia screening into the preoperative assessment for gastroesophageal reflux disease patients. For those diagnosed with sarcopenia, a targeted prehabilitation protocol emphasizing nutritional support and physical training could be implemented to potentially enhance surgical tolerance and recovery outcomes. Future studies are warranted to validate the efficacy of such prehabilitation strategies and to further investigate the precise molecular mechanisms through which sarcopenia impedes postoperative recovery.

Frontiers in SurgeryVol. 13
Hengshui University (CN), First Affiliated Hospital of Hebei Medical University (CN)
Hebei Medical University
Good health and well-being
Openalex Percentile: Top 24%
Gastroesophageal reflux and treatments
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