Balloon catheter plus concurrent vaginal misoprostol versus vaginal misoprostol alone for cervical ripening in induction of labor: A systematic review and an individual participant data meta‐analysis of randomized controlled trials
Based on trustworthy data, the current evidence does not suggest that one method is superior to the other for the effectiveness of the combined balloon catheter with concurrent low-dose vaginal misoprostol versus low-dose vaginal misoprostol alone. At present, we are uncertain about the safety of using the combined method due to low data retrieval and trustworthiness concerns among the underlying trials. The results could slightly favor the combined method due to reduced hyperstimulation and meconium-stained liquor.
Authors
- Syeda Batool Mazhar (ORCID: https://orcid.org/0000-0001-9531-8131)
- Sidra Gilani
- Marino Romero Ramírez
- Tarakeswari Surapaneni
- Davies K. Kibii
- W. Q. Li
- Malitha Patabendige (ORCID: https://orcid.org/0000-0002-4092-7092)
- Alfred Osoti (ORCID: https://orcid.org/0000-0002-2049-3100)
- F. L. Chan
- Ben W. Mol
- Zainab Al‐Ibraheemi
- Daniel L. Rolnik
- Philip Ayieko
- Angeles Vives Argilagos
Institutions
- University of Nairobi (KE)
- University of Washington (US)
- UNSW Sydney (AU)
- London School of Hygiene & Tropical Medicine (GB)
- Fernandez Hospital (IN)
- Consorci Sanitari de Terrassa (ES)
- Mount Sinai Hospital (US)
- National Centre for Clinical Research on Emerging Drugs (AU)
- St John of God Hospital (AU)
- Pakistan Institute of Medical Sciences (PK)
- Monash University (AU)
Publication Details
- Journal
- International Journal of Gynecology & Obstetrics
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1002/ijgo.70949
- Primary Topic
- Maternal and Perinatal Health Interventions
- Type
- article
- Field-Weighted Citation Impact
- 0.00