COVID-19 lockdown and association with placental function – a quasi-experimental analysis
Being exposed to COVID 19 lockdown was associated with a slight increase in hypertensive disorders of pregnancy, including pre-eclampsia, but a counterintuitive trend towards lower risk for small-for-gestational-age. Because the effect was most clear in the first trimester, the nationwide lockdown therefore seems to have a complex effect on the in-utero environment through the placenta.
Authors
- Jeremy A. Labrecque (ORCID: https://orcid.org/0000-0002-1028-2158)
- Tom Van Ourti (ORCID: https://orcid.org/0000-0003-0110-770X)
- Benjamin Gravesteijn
- Lilian L. Peters (ORCID: https://orcid.org/0000-0003-2342-0799)
- Nienke W Boderie (ORCID: https://orcid.org/0000-0002-1600-380X)
- Jasper V. Been (ORCID: https://orcid.org/0000-0002-4907-6466)
- C. Groot (ORCID: https://orcid.org/0000-0001-6940-0289)
- Ben Willem Mol
- Ank de Jonge
- Loes Cm Bertens
- Jeroen van Dillen
- Sam Schoenmakers
- Thomas van den Akker
- Kim Vanden Auweele
- Sylvia Oberman
- Martijn Oudijk
- Zainulareb Zohra
- Brenda M. Kazemier
Institutions
- University Medical Center Groningen (NL)
- Radboud University Nijmegen (NL)
- Leiden University Medical Center (NL)
- Erasmus MC (NL)
- Radboud University Medical Center (NL)
- University Medical Center Utrecht (NL)
- Duchenne Parent Project (NL)
- Erasmus MC - Sophia Children’s Hospital (NL)
- Amsterdam University Medical Centers (NL)
- Katholieke Pabo Zwolle (NL)
- Monash University (AU)
- University of Amsterdam (NL)
- Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Pregnancy Hypertension
- Published
- 2026-03-11
- DOI
- https://doi.org/10.1016/j.preghy.2026.101452
- Primary Topic
- COVID-19 Impact on Reproduction
- Type
- article
- Field-Weighted Citation Impact
- 0.00