Cancer Risk in Solid Organ Transplant Recipients With a Pretransplant Cancer History
This cohort study found that SOT recipients with pretransplant cancer had an elevated risk of posttransplant cancer, particularly of the same cancer type. These patterns likely reflect shared genetic or environmental risk factors. Among SOT recipients who had kidney, liver, or lung cancer before transplant, posttransplant cancer of the same organ may be associated with the underlying end-stage organ disease. Targeted cancer prevention and screening could benefit SOT recipients who have survived a cancer diagnosis before a transplant.
Authors
- Ajay Israni
- L. Morton
- Tabassum Z. Insaf (ORCID: https://orcid.org/0000-0003-4725-2515)
- Q. Luo
- E. Engels
- Baozhen Qiao (ORCID: https://orcid.org/0000-0002-8407-7835)
- Jun Tao (ORCID: https://orcid.org/0000-0002-2226-765X)
- C. F. Lynch
- Shyfuddin Ahmed
- Ruth M. Pfeiffer
- Daniela Ramirez-Aguilar
Institutions
- University of Iowa (US)
- New York State Department of Health (US)
- National Institutes of Health (US)
- National Cancer Institute (US)
- Arkansas Department of Health (US)
- The University of Texas Medical Branch at Galveston (US)
Publication Details
- Journal
- JAMA Oncology
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1001/jamaoncol.2026.0206
- Primary Topic
- Viral-associated cancers and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00