Molecular Characterization of <i>KLK2</i> RNA Expression in Prostate Cancer
This large-scale clinico-genomic analysis reveals distinct KLK2 expression patterns across prostate cancer histologies, tumor sites, and clinical states. These findings provide a molecular framework understanding KLK2 as a therapeutic target in prostate cancer.
Authors
- Neeraj Agarwal
- Charles G. Drake (ORCID: https://orcid.org/0000-0001-9610-3677)
- Brent Shane Rose (ORCID: https://orcid.org/0000-0002-3197-9552)
- Brent Rupnow (ORCID: https://orcid.org/0000-0002-0234-0039)
- Himisha Beltran (ORCID: https://orcid.org/0000-0003-3259-2226)
- Shayan Nazari (ORCID: https://orcid.org/0000-0001-8487-5274)
- Rana R. McKay (ORCID: https://orcid.org/0000-0002-0581-7963)
- Subhasree Basu (ORCID: https://orcid.org/0009-0008-0969-800X)
- Norm D. Smith
- Deepak Kilari
- Rohan Garje
- Pedro C. Barata
- A. Elliott
- Emmanuel S. Antonarakis
- Michael C. Haffner
- Aditya Bagrodia
- Colm Morrissey
Institutions
- University of Minnesota (US)
- Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa (ZA)
- Johnson & Johnson (United States) (US)
- University of San Diego (US)
- University of Washington (US)
- Medical College of Wisconsin (US)
- University of Minnesota System (US)
- Huntsman Cancer Institute (US)
- University of California San Diego (US)
- Fred Hutch Cancer Center (US)
- Baptist Health South Florida (US)
- Springhouse (US)
- Dana-Farber Cancer Institute (US)
- University Hospitals Seidman Cancer Center (US)
- Caris Life Sciences (United States) (US)
- New Mexico Cancer Center (US)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1158/1078-0432.ccr-25-4293
- Primary Topic
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Type
- article
- Field-Weighted Citation Impact
- 0.00