Safety and Efficacy of Esomeprazole-Containing Regimens for Helicobacter pylori Eradication: A Multicenter Retrospective Study
Esomeprazole-containing regimens are effective and well tolerated for H. pylori eradication. Bismuth- and doxycycline-based quadruple therapies achieved the highest eradication rates, particularly in treatment-naïve patients. Tailored strategies incorporating bismuth or quadruple therapy may benefit patients with prior treatment failures or from lower socioeconomic backgrounds. Further research should consider regional resistance patterns and prospective designs.
Authors
- Mohammed Tag-Adeen
- Tamer Haydara (ORCID: https://orcid.org/0000-0003-3385-4582)
- Nermeen Abdeen (ORCID: https://orcid.org/0000-0003-3272-4233)
- Sameh A. Lashen (ORCID: https://orcid.org/0000-0002-8599-1338)
- Sally Waheed Elkhadry (ORCID: https://orcid.org/0000-0001-9305-3045)
- Mina Tharwat
- Ahmed Bahaa (ORCID: https://orcid.org/0000-0001-6690-0536)
- Mohammad Aamr
- Omar Ashoush
- Mohamed Malak (ORCID: https://orcid.org/0000-0002-4373-6259)
- Hatem Elalfy (ORCID: https://orcid.org/0000-0002-5602-0989)
- Marwan Elgohary
- Ossama Ashraf Ahmed
- Mohamed Abdelghani (ORCID: https://orcid.org/0000-0003-1370-5336)
- Mohamed Omar Abdelmalek
- Sherief M Abdel-salam
- Ahmed Abdelaziz
- Mohamed M. Mabrouk
- Mohamed Alboraie
- Essam Aly Hassan
Publication Details
- Journal
- Digestive Diseases
- Published
- 2026-03-11
- DOI
- https://doi.org/10.1159/000551339
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00