NFIC suppressed the development of Glioma via modulating the balance of SHP2/PI3K and NF-κB/PTEN Signaling
The overexpression of NFIC has the capacity to inhibit the PI3K/AKT signalling pathway, a process facilitated by the promotion of the expression of OGN and PTEN. This, consequently, results in the inhibition of glioma proliferation and development.
Authors
- Hongen Bao
- Youle Su
- Huiru Bai (ORCID: https://orcid.org/0000-0002-2626-1861)
- Fei Wang (ORCID: https://orcid.org/0000-0002-5192-0689)
- Changwu Dou
- Kun Liu (ORCID: https://orcid.org/0000-0001-5807-0501)
- Fenjun Jiang
- Naikang Gao
Institutions
- Shaoxing No.6 People's Hospital (CN)
- Shaoxing People's Hospital (CN)
- Inner Mongolia Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-03-11
- DOI
- https://doi.org/10.1371/journal.pone.0341816
- Primary Topic
- NF-κB Signaling Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00