Efficacy and safety of edaravone sublingual tablet for patients with cerebral small vessel disease-related cognitive impairment: study protocol for a multicentre, randomised, double-blind, placebo-controlled trial

This trial will evaluate the efficacy and safety of EST in patients with CSVD-CI, potentially offering a new treatment strategy for this condition.

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Publication Details

Journal
Stroke and Vascular Neurology
Published
2026-03-11
DOI
https://doi.org/10.1136/svn-2025-004198
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Efficacy and safety of edaravone sublingual tablet for patients with cerebral small vessel disease-related cognitive impairment: study protocol for a multicentre, randomised, double-blind, placebo-controlled trial

X. Ronald Zhu, Weidong Ling, Lei Yu, Lili Huang et al.
Stroke and Vascular Neurology
Dementia and Cognitive Impairment Research
article

Efficacy and safety of edaravone sublingual tablet for patients with cerebral small vessel disease-related cognitive impairment: study protocol for a multicentre, randomised, double-blind, placebo-controlled trial

X. Ronald Zhu, Weidong Ling, Lei Yu, Lili Huang, Yuting Mo, Hailan Meng, Rong Rong, Qing Ye, Yue Cheng, Haifeng Chen, Lai Qian, Yun Xu, Xin Zhang
article en

Abstract

This trial will evaluate the efficacy and safety of EST in patients with CSVD-CI, potentially offering a new treatment strategy for this condition.

Stroke and Vascular Neurology
Nanjing Brain Hospital (CN), Nanjing Drum Tower Hospital (CN), Nanjing University (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 33%
Dementia and Cognitive Impairment Research
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