The use of the S-Caine patch is safe and feasible in children younger than three: a nonrandomised clinical trial
• The S-Caine patch provides a safe, non-invasive analgesic option for children under three, with plasma lidocaine levels well below strict safety thresholds and only minor transient local reactions, improving procedural comfort and reducing reliance on systemic pain interventions.
Authors
- Katrien Lanckmans (ORCID: https://orcid.org/0000-0001-7992-6364)
- Gerlant van Berlaer (ORCID: https://orcid.org/0000-0003-3674-9083)
- Tom De Potter (ORCID: https://orcid.org/0000-0001-9717-3917)
- Britt Anciaux
- Ronald Buyl
Institutions
- Vrije Universiteit Brussel (BE)
- Office of Readiness and Response (US)
- Universitair Ziekenhuis Brussel (BE)
- Pro Persona (NL)
Publication Details
- Journal
- European Journal of Pediatrics
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1007/s00431-026-06826-5
- Primary Topic
- Pediatric Pain Management Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00