The impact of radiation-induced temporal lobe injury on cognition and structure across the whole brain in nasopharyngeal carcinoma patients
Compared to nRI-TLI patients, RI-TLI patients exhibit more severe cognitive impairment alongside decreased GM and WM in both the temporal lobe and prefrontal regions. The observed structural alterations are associated with the severity of cognitive deficits and may serve as potential neuroimaging markers for RI-TLI.
Authors
- Yizhi Ge (ORCID: https://orcid.org/0000-0001-8349-0970)
- Yesong Guo (ORCID: https://orcid.org/0000-0002-7064-2346)
- Pengwei Yan
- Jianfeng Wu
- Jingjing Han
- Siwen Liu
- Peng Xie
Institutions
- Jiangsu Cancer Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- IBRO Neuroscience Reports
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1016/j.ibneur.2026.03.006
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Government of Jiangsu Province