Dental pulp in health and disease -a review with notes on basic three-dimensional tissue organization

<p>In health, the dental pulp functions as a sensory organ, detecting external stimuli such as temperature, pressure, and chemical irritants. The pulp is also involved in dentinogenesis. This process helps maintain tooth integrity throughout an individual's lifetime. Furthermore, the dental pulp acts as a reservoir for stem cells, which have the potential to differentiate into various cell types, including odontoblasts and fibroblasts. This regenerative capacity is a cornerstone of dental pulp's role in health, aiding in the repair of minor injuries or damages to the tooth structure. Dental pulp can become vulnerable to various diseases and conditions, potentially leading to pain, infection, and tooth loss. Pulpitis, characterized by pulp inflammation, often results from untreated dental caries (cavities) or trauma. If left untreated, pulpitis can be irreversible, necessitating root canal therapy to remove the affected tissue. In severe cases, when infection breaches the pulp chamber, an abscess can form, posing significant health risks if not promptly addressed. Furthermore, systemic diseases, such as diabetes, can impact the pulp's vascularization and regenerative capabilities, affecting overall dental health. Dental professionals must understand the intricate relationship between dental pulp and health. Timely diagnosis and appropriate management of pulp-related conditions are crucial to preserving oral health and preventing systemic complications. This review also includes a note on the third dimension of the basic organization of dental pulp.</p>

Authors

Publication Details

Journal
International Journal of Clinicopathological Correlation
Published
2025-06-30
DOI
https://doi.org/10.56501/intjclinicopatholcorrel.v9i1.1249.
Primary Topic
Endodontics and Root Canal Treatments
Type
article
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article

Dental pulp in health and disease -a review with notes on basic three-dimensional tissue organization

Bhavani Nagendra Sangala, Sandhya Tamgadge, Avinash Tamgadge, Pratibha Kavale et al.
International Journal of Clinicopathological Correlation
Endodontics and Root Canal Treatments
article

Dental pulp in health and disease -a review with notes on basic three-dimensional tissue organization

Bhavani Nagendra Sangala, Sandhya Tamgadge, Avinash Tamgadge, Pratibha Kavale, Bhagyashree P Agre
article en

Abstract

<p>In health, the dental pulp functions as a sensory organ, detecting external stimuli such as temperature, pressure, and chemical irritants. The pulp is also involved in dentinogenesis. This process helps maintain tooth integrity throughout an individual's lifetime. Furthermore, the dental pulp acts as a reservoir for stem cells, which have the potential to differentiate into various cell types, including odontoblasts and fibroblasts. This regenerative capacity is a cornerstone of dental pulp's role in health, aiding in the repair of minor injuries or damages to the tooth structure. Dental pulp can become vulnerable to various diseases and conditions, potentially leading to pain, infection, and tooth loss. Pulpitis, characterized by pulp inflammation, often results from untreated dental caries (cavities) or trauma. If left untreated, pulpitis can be irreversible, necessitating root canal therapy to remove the affected tissue. In severe cases, when infection breaches the pulp chamber, an abscess can form, posing significant health risks if not promptly addressed. Furthermore, systemic diseases, such as diabetes, can impact the pulp's vascularization and regenerative capabilities, affecting overall dental health. Dental professionals must understand the intricate relationship between dental pulp and health. Timely diagnosis and appropriate management of pulp-related conditions are crucial to preserving oral health and preventing systemic complications. This review also includes a note on the third dimension of the basic organization of dental pulp.</p>

International Journal of Clinicopathological CorrelationVol. 9(1)
Good health and well-being
Openalex Percentile: Top 22%
Endodontics and Root Canal Treatments
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Dental pulp in health and disease -a review with notes on basic three-dimensional tissue organization — Bhavani Nagendra Sangala, Sandhya Tamgadge, et al. · International Journal of Clinicopathological Correlation (2025) | TGRS Research Map | TGRS