Clinical outcomes and patient-reported measures in HCV care: Insight from a longitudinal prospective study in a large Italian region
This study highlights the importance of integrating clinical and patient-reported data in monitoring HCV care. High SVR rates confirm the effectiveness of DAAs, while PROMs and PREMs provide valuable insight into patient engagement and equity of access. Stratified analyses reveal the need for tailored approaches across care pathways, and high-risk populations require special attention. Embedding patient voice in evaluation fosters a more responsive, people-centered health system, advancing progress toward HCV elimination.
Authors
- Ilaria Corazza (ORCID: https://orcid.org/0000-0002-1798-8348)
- Giaele Moretti (ORCID: https://orcid.org/0000-0001-5838-448X)
- Milena Vainieri (ORCID: https://orcid.org/0000-0002-0914-4487)
- Lara Tavoschi (ORCID: https://orcid.org/0000-0002-2217-4664)
- Erica De Vita (ORCID: https://orcid.org/0000-0002-2659-0905)
- Maria Paola Tramonti Fantozzi (ORCID: https://orcid.org/0000-0001-5146-4997)
- on behalf of OPT-HepaC project team
Institutions
- University of Pisa (IT)
- Scuola Superiore Sant'Anna (IT)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-03-11
- DOI
- https://doi.org/10.1371/journal.pone.0343936
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Università degli Studi di Siena
- Università degli Studi di Firenze
- Università di Pisa
- Regione Toscana
- Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze