Quantify unmet medical need across the disease landscape – A large language model-based methodology

This accessible, scalable methodology enables funders and researchers, across governments, universities, healthcare organizations, and disease groups to tailor prioritization efforts according to unmet medical need in the context of their organizational objectives, by selecting appropriate criteria and weighting of those criteria. This method creates a pragmatic and transparent tool to streamline research prioritization. Future research should consider expanding the disease set size used to create scores.