Effect of Substance Abuse on Suicidal Behaviors Among People Living With HIV: 11-Year Cohort Study

The findings indicate that substance abusers face a nearly twofold higher risk of suicide than nonusers, with significant socioeconomic disparities evident. Moreover, sleep disturbances was identified as a critical mediator in the relationship between substance abuse and suicide. These findings provide valuable insights to help improve clinical practices and policy development efforts aimed at preventing suicidal behaviors and improving the well-being of PLHIV struggling with substance abuse globally.