Well preserved versus severely impaired memory 10-44 years after temporal lobe epilepsy surgery: “How did the patients get there?”
Many years after temporal lobe epilepsy surgery, 45% of patients achieved continuous seizure freedom and 20% late seizure freedom. Only 9% reported late memory decline. Verbal memory tended to decline shortly after surgery but showed recovery over time, whereas figural memory more often declined later. These patterns suggest late mechanisms of functional recovery, compensation, and reorganization.
Authors
- Jugoslav Ivanović (ORCID: https://orcid.org/0000-0002-0920-2341)
- Morten I. Lossius (ORCID: https://orcid.org/0000-0002-5982-7737)
- Annette Holth Skogan (ORCID: https://orcid.org/0000-0002-8215-6396)
- Einar Heminghyt
- Kristin Å. Alfstad (ORCID: https://orcid.org/0009-0000-6981-4377)
- Eli Berit Kyte (ORCID: https://orcid.org/0009-0001-6852-026X)
- Christoph Helmstaedter
Institutions
- Oslo University Hospital (NO)
- University of Bonn (DE)
- University of Oslo (NO)
- National Hospital (IN)
Publication Details
- Journal
- Seizure
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1016/j.seizure.2026.03.008
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00