Influence of Synovial Fluid Biochemical Markers on Clinical Outcomes Following Arthroscopic and Non-Arthroscopic Patients with Knee Osteoarthritis
Our findings support a two-stage therapeutic strategy in which UC-MSC secretome first alleviates inflammation, followed by UC-MSCs to promote cartilage regeneration. Post-injection rehabilitation or repeated MSC dosing may further enhance treatment efficacy, highlighting the potential of MSC-based therapies for knee OA management.
Authors
- Rima Haifa
- Cynthia Retna Sartika
- Lestari Mahardika Urbaningrum (ORCID: https://orcid.org/0009-0008-4344-5292)
- Ditta Kalyani Devi
- Karina Kalasuba (ORCID: https://orcid.org/0009-0007-4289-2608)
- Keri Lestari
- Yanuarso
Institutions
- Gatot Soebroto Army Hospital (ID)
- Universitas 17 Agustus 1945 Jakarta (ID)
- Padjadjaran University (ID)
Publication Details
- Journal
- Orthopedic Reviews
- Published
- 2026-03-13
- DOI
- https://doi.org/10.52965/001c.158292
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00