Symptom profiles in the late reproductive stage, earlier premenopause and early perimenopause in the absence of vasomotor symptoms: a cross-sectional study

Premenopausal women with regular menstrual cycles reporting changed menstrual flow but no VMS differ little from those without VMS and no change in menstrual flow. This indicates that change in flow alone is not a clear indicator of commencement of the menopause transition.