Mendelian randomization reveals DNA methylation–related pyroptosis genes associated with psoriasis risk
This multi-omics analysis reveals that pyroptosis-related genes, particularly ADAR, DNMT3B, PROM2, KIF11, and NFKB1, may be involved in psoriasis development, providing important insights into its molecular mechanisms and potential therapeutic targets.
Authors
- Cuiping Shi
- Wenwu Dong
Institutions
- Southern University of Science and Technology (CN)
- Southern Medical University Shenzhen Hospital (CN)
- Shenzhen Second People's Hospital (CN)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1186/s13148-026-02063-7
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00