Saddle Pulmonary Embolism and Deep Vein Thrombosis Following Foot and Ankle Surgery While on Prophylactic Lovenox: A Case Report

Venothromboembolic (VTE) events are considered rare complications following foot and ankle surgery. Most instances of VTE following surgical procedures occur in particularly high-risk patient populations; therefore, VTE prophylactic anticoagulation is initiated based on risk/benefit stratification for each individual patient undergoing foot and ankle surgery. We present a case report on a 40-year-old male who underwent isolated Lisfranc ligament repair and subsequently developed an acute saddle pulmonary embolism and deep vein thrombosis 1 month postoperatively. The patient was on prophylactic Lovenox, yet still developed a life-threatening complication. The patient was found to be on a selective estrogen receptor modulator for the off-label treatment of male infertility. This medication, surgical intervention, and a period of non-weight bearing are believed to be contributory to the patient's relatively increased hypercoagulable state. This case depicts a rare complication of foot and ankle surgery and highlights the importance of VTE prophylaxis during the postoperative period.

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Publication Details

Journal
Journal of the American Podiatric Medical Association
Published
2026-03-11
DOI
https://doi.org/10.3390/japma116020012
Primary Topic
Venous Thromboembolism Diagnosis and Management
Type
article
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article

Saddle Pulmonary Embolism and Deep Vein Thrombosis Following Foot and Ankle Surgery While on Prophylactic Lovenox: A Case Report

Robert W. Mendicino, Sara Judickas, Joseph R. Brown
Journal of the American Podiatric Medical Association
Venous Thromboembolism Diagnosis and Management
article

Saddle Pulmonary Embolism and Deep Vein Thrombosis Following Foot and Ankle Surgery While on Prophylactic Lovenox: A Case Report

Robert W. Mendicino, Sara Judickas, Joseph R. Brown
article en

Abstract

Venothromboembolic (VTE) events are considered rare complications following foot and ankle surgery. Most instances of VTE following surgical procedures occur in particularly high-risk patient populations; therefore, VTE prophylactic anticoagulation is initiated based on risk/benefit stratification for each individual patient undergoing foot and ankle surgery. We present a case report on a 40-year-old male who underwent isolated Lisfranc ligament repair and subsequently developed an acute saddle pulmonary embolism and deep vein thrombosis 1 month postoperatively. The patient was on prophylactic Lovenox, yet still developed a life-threatening complication. The patient was found to be on a selective estrogen receptor modulator for the off-label treatment of male infertility. This medication, surgical intervention, and a period of non-weight bearing are believed to be contributory to the patient's relatively increased hypercoagulable state. This case depicts a rare complication of foot and ankle surgery and highlights the importance of VTE prophylaxis during the postoperative period.

Journal of the American Podiatric Medical AssociationVol. 116(2)
Grant Medical Center (US), St Francis Medical Center (US), Centralia College (US)
Good health and well-being
Openalex Percentile: Top 30%
Venous Thromboembolism Diagnosis and Management
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