Nutrient and heat stress induce changes to the solubility of predicted prion-like proteins in Dictyostelium discoideum
During heat and nutrient stress Dictyostelium have numerous proteins that have decreased solubility. Among these proteins, predicted prion-like proteins are enriched and the presence of a polyglutamine tract is sufficient to cause decreased solubility in a polyglutamine length dependent manner.
Authors
- Erik J. Soderblom (ORCID: https://orcid.org/0000-0002-6765-1786)
- Kanesha L. Travis
- Yaneli Guerra-Hernandez
- Felicia N. Williams
- K. Matthew Scaglione
Institutions
- University of North Carolina at Chapel Hill (US)
- Duke University (US)
- Abterra Biosciences (United States) (US)
Publication Details
- Journal
- BMC Molecular and Cell Biology
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1186/s12860-026-00582-y
- Primary Topic
- Biotin and Related Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00