Genome wide association study of vaginal microbiota genetic diversity in French women

This is one of the first GWAS to use microbial genetic data instead of symptoms to characterise the vaginal microbiota. However, it remains limited because of the size of our cohort and our results call for more powered studies in terms of participants and genome coverage.

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Publication Details

Journal
Open Research Europe
Published
2026-03-11
DOI
https://doi.org/10.12688/openreseurope.20462.2
Primary Topic
Reproductive tract infections research
Type
article
Field-Weighted Citation Impact
0.00
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article

Genome wide association study of vaginal microbiota genetic diversity in French women

Christelle Graf, Vincent Tribout, Vincent Pedergnana, Claire Bernat et al.
Open Research Europe
Reproductive tract infections research
article

Genome wide association study of vaginal microbiota genetic diversity in French women

Christelle Graf, Vincent Tribout, Vincent Pedergnana, Claire Bernat, Nicolas Tessandier, Massilva Rahmoun, Nathalie Boulle, Tsukushi Kamiya, Samuel Alizon, Sophie Grasset, Soraya Groc, Carmen Lía Murall, Marine Bonneau, Vincent Foulongne, Michel Segondy, Jacques Ravel, Jean-François Deleuze, Christian Selinger, Jacques Reynes, Vanina Boué
article en

Abstract

This is one of the first GWAS to use microbial genetic data instead of symptoms to characterise the vaginal microbiota. However, it remains limited because of the size of our cohort and our results call for more powered studies in terms of participants and genome coverage.

Open Research EuropeVol. 5
University of Maryland, Baltimore (US), Centre National de la Recherche Scientifique (FR), Inserm (FR), Swiss Tropical and Public Health Institute (CH), Public Health Agency of Canada (CA), Université de Montpellier (FR), Université Paris-Saclay (FR), Centre National de Recherche en Génomique Humaine (FR), Centre Hospitalier Universitaire de Montpellier (FR), Centre Interdisciplinaire de Recherche en Biologie (FR), Institut de Génomique Fonctionnelle (FR), Institut de Recherche pour le Développement (FR)
Gender equality
Openalex Percentile: Top 26%
Reproductive tract infections research
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