Impact of Borderline Resectable Criteria on Hepatocellular Carcinoma Treatment From the Perspective of Tumor Burden

Macrovascular invasion significantly impacted prognosis in patients undergoing hepatectomy, for both BR1 and BR2, whereas any of the tumor factors did not affect the prognosis of patients receiving systemic chemotherapy. Tumor burden correlated with prognosis in the entire cohort but not in chemotherapy responders, suggesting effective treatment may overcome poor prognostic indicators.

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Publication Details

Journal
World Journal of Surgery
Published
2026-03-12
DOI
https://doi.org/10.1002/wjs.70287
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
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article

Impact of Borderline Resectable Criteria on Hepatocellular Carcinoma Treatment From the Perspective of Tumor Burden

Eisuke Ueshima, Jun Ishida, Nobuaki Ishihara, Keitaro Sofue et al.
World Journal of Surgery
Hepatocellular Carcinoma Treatment and Prognosis
article

Impact of Borderline Resectable Criteria on Hepatocellular Carcinoma Treatment From the Perspective of Tumor Burden

Eisuke Ueshima, Jun Ishida, Nobuaki Ishihara, Keitaro Sofue, Hidetoshi Gon, Masaki Omori, Yuzo Kodama, Yoshimi Fujishima, Takumi Fukumoto, Hiroaki Yanagimoto, Masahiro Kido, Shohei Komatsu, Yoshihide Nanno, Toshifumi Tada, Kenji Fukushima, Takanori Matsuura, Takeshi Urade
article en

Abstract

Macrovascular invasion significantly impacted prognosis in patients undergoing hepatectomy, for both BR1 and BR2, whereas any of the tumor factors did not affect the prognosis of patients receiving systemic chemotherapy. Tumor burden correlated with prognosis in the entire cohort but not in chemotherapy responders, suggesting effective treatment may overcome poor prognostic indicators.

World Journal of Surgery
Kobe Medical Center (JP), Kobe University Hospital (JP), Kobe University (JP)
No poverty
Openalex Percentile: Top 28%
Hepatocellular Carcinoma Treatment and Prognosis
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