The association between prescribed hormonal contraception and multiple sclerosis risk: a systematic review and meta-analysis
No statistically significant association between HC use and MS risk was observed. The meta-analyses indicate a possible increased risk warranting further investigation. Given that heterogeneity was high and only three of the included studies were classed as high-quality, a well-designed study is needed to clarify this association.
Authors
- Sonia Gran (ORCID: https://orcid.org/0000-0002-2443-5100)
- Christopher R. Tench (ORCID: https://orcid.org/0000-0001-9067-0494)
- Bruno R Gran
- Jessica McDonald
- Priya Sharma
- Radu Tanasescu
- Ruth Dobson
Institutions
- Nottingham University Hospitals NHS Trust (GB)
- University of Nottingham (GB)
- Queen Mary University of London (GB)
Publication Details
- Journal
- Neurological Sciences
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1007/s10072-026-08953-1
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00