Toxicity profile of supratherapeutic loperamide: a systematic review and dose–response analysis
Patients presenting with supratherapeutic loperamide exposure appear to be at high risk for life-threatening dysrhythmias, and close cardiac monitoring should be broadly considered in this population. Management options include appropriate antiarrhythmic and cardiocirculatory support measures.
Authors
- Elias Bekka (ORCID: https://orcid.org/0000-0001-9958-7769)
- Stefan Weiler (ORCID: https://orcid.org/0000-0003-1087-7597)
- Manuel Haschke (ORCID: https://orcid.org/0000-0003-1846-8640)
- Evangelia Liakoni (ORCID: https://orcid.org/0000-0002-2239-1378)
- Adrian Martinez-De la Torre (ORCID: https://orcid.org/0000-0002-3155-7421)
Institutions
- University of Lucerne (CH)
- University Hospital of Bern (CH)
- ETH Zurich (CH)
- University Hospital of Zurich (CH)
- Swiss Paraplegic Research (CH)
Publication Details
- Journal
- Clinical Toxicology
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1080/15563650.2026.2634757
- Primary Topic
- Poisoning and overdose treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00