Allogeneic Hematopoietic Cell Transplantation Using Post‐Transplant Cyclophosphamide in Patients With Large Paroxysmal Nocturnal Hemoglobinuria Clones

This study, representing the largest reported experience with PTCy-based HSCT for PNH, suggests that this platform is feasible and associated with excellent survival and a promising GvHD profile. These preliminary findings support further investigation of PTCy in transplant strategies for PNH.

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Publication Details

Journal
European Journal Of Haematology
Published
2026-03-12
DOI
https://doi.org/10.1111/ejh.70162
Primary Topic
Complement system in diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Allogeneic Hematopoietic Cell Transplantation Using Post‐Transplant Cyclophosphamide in Patients With Large Paroxysmal Nocturnal Hemoglobinuria Clones

Bin Fu, Zheng Wang, Yú Chen, Ling Nie et al.
European Journal Of Haematology
Complement system in diseases
article

Allogeneic Hematopoietic Cell Transplantation Using Post‐Transplant Cyclophosphamide in Patients With Large Paroxysmal Nocturnal Hemoglobinuria Clones

Bin Fu, Zheng Wang, Yú Chen, Ling Nie, Mingyang Deng, Xin Li, Ping Zhu, Yajing Xu, Qiangsheng Weng, Can Liu
article en

Abstract

This study, representing the largest reported experience with PTCy-based HSCT for PNH, suggests that this platform is feasible and associated with excellent survival and a promising GvHD profile. These preliminary findings support further investigation of PTCy in transplant strategies for PNH.

European Journal Of Haematology
Central South University (CN), Hunan Provincial People's Hospital (CN), Chenzhou First People's Hospital (CN), Second Xiangya Hospital of Central South University (CN), Third Xiangya Hospital (CN), Xiangya Hospital Central South University (CN)
Good health and well-being
Openalex Percentile: Top 25%
Complement system in diseases
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