Revealing and quantifying polyclonal anti‐A, B specificity in <scp>ABO</scp> histo‐blood groups

Anti-A,B is a much more complex antibody than current understanding, and shows a range of activity over a large continuum, which includes in vitro detectable anti-A,B-like antibodies in non-group O samples. The ability to measure anti-A,B independently of anti-A and anti-B levels may be useful in evaluating clinical associations.

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Publication Details

Journal
Transfusion
Published
2026-03-12
DOI
https://doi.org/10.1111/trf.70175
Primary Topic
Blood groups and transfusion
Type
article
Field-Weighted Citation Impact
0.00
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article

Revealing and quantifying polyclonal anti‐A, B specificity in ABO histo‐blood groups

Steve Henry, Ivan M. Ryzhov, Polina Obukhova, Tatiana V. Tyrtysh et al.
Transfusion
Blood groups and transfusion
article

Revealing and quantifying polyclonal anti‐A, B specificity in ABO histo‐blood groups

Steve Henry, Ivan M. Ryzhov, Polina Obukhova, Tatiana V. Tyrtysh, Holly Perry, N. V. Bovin, Suvro Sankha Datta
article en

Abstract

Anti-A,B is a much more complex antibody than current understanding, and shows a range of activity over a large continuum, which includes in vitro detectable anti-A,B-like antibodies in non-group O samples. The ability to measure anti-A,B independently of anti-A and anti-B levels may be useful in evaluating clinical associations.

Transfusion
Auckland University of Technology (NZ), Tata Medical Center (IN), Institute of Bioorganic Chemistry (RU), University of Otago (NZ)
Openalex Percentile: Top 24%
Blood groups and transfusion
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