Magnetization transfer ratio is decreased in the sciatic nerve of patients with relapsing-remitting multiple sclerosis
Sciatic nerve MTR differentiates between RRMS patients and controls and correlates with important clinical and electrophysiologic data suggesting clinical relevance of an MTR decrease in the PNS. Our results provide further evidence of peripheral nerve involvement in RRMS and point towards peripheral co-demyelination.
Authors
- Brigitte Wildemann (ORCID: https://orcid.org/0000-0002-5389-3338)
- Martin Bendszus (ORCID: https://orcid.org/0000-0002-9094-6769)
- Andrea Viehöver
- John M. Hayes (ORCID: https://orcid.org/0000-0002-5677-2216)
- Georges Sam (ORCID: https://orcid.org/0000-0003-0255-1722)
- Olivia Fösleitner (ORCID: https://orcid.org/0000-0001-6392-5180)
- Sabine Heiland (ORCID: https://orcid.org/0000-0002-2796-3451)
- Jennifer C. Hayes (ORCID: https://orcid.org/0000-0002-6254-9192)
- Markus Weiler
- Anysia Poncelet
- Kira Göldner
- Mirjam Korporal-Kuhnke
Institutions
- Heidelberg University (DE)
- University of Michigan (US)
- University Hospital Heidelberg (DE)
- Klinikum Darmstadt (DE)
- Michigan Medicine (US)
Publication Details
- Journal
- European Journal of Radiology
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1016/j.ejrad.2026.112783
- Primary Topic
- Transcranial Magnetic Stimulation Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00