Prognostic accuracy of severity grading score and severity scoring index for predicting severe outcomes in Crimean-Congo hemorrhagic fever: a systematic review and meta-analysis

Both scores are clinically useful prognostic tools in Crimean-Congo hemorrhagic fever, but with distinct roles. Severity Grading Score is better suited for confirming high-risk status, while Severity Scoring Index performs better as an early triage tool to identify patients at risk of death. Prospective head-to-head validation with standardized outcomes is warranted to guide their incorporation into clinical triage protocols and management guidelines.