Precision management of radiotherapy interruption in locoregionally advanced nasopharyngeal carcinoma: Induction chemotherapy counteracts the survival impact in high-risk patients defined by a novel model

The developed model effectively identified high-risk NPC patients vulnerable to RTI ≥5 days, with IC shown to mitigate this risk. These findings support the implementation of risk-stratified treatment strategies and proactive IC use to counter unavoidable treatment delays.

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Publication Details

Journal
Translational Oncology
Published
2026-03-12
DOI
https://doi.org/10.1016/j.tranon.2026.102725
Primary Topic
Head and Neck Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Precision management of radiotherapy interruption in locoregionally advanced nasopharyngeal carcinoma: Induction chemotherapy counteracts the survival impact in high-risk patients defined by a novel model

Yue Yao, Wenkui Li, Zhong-Guo Liang, Li-ting Ling et al.
Translational Oncology
Head and Neck Cancer Studies
article

Precision management of radiotherapy interruption in locoregionally advanced nasopharyngeal carcinoma: Induction chemotherapy counteracts the survival impact in high-risk patients defined by a novel model

Yue Yao, Wenkui Li, Zhong-Guo Liang, Li-ting Ling, Jing-wen Cheng, Qing-qing Nong, Xue-wen Luo, Ying Guan, Ling Li, Song Qu, Ye (Lennon) Li, Xiao-dong Zhu, Bo-lin Zhu, Min Bi, Li-Qing Zhou, Bin Deng, Fang Su
article en

Abstract

The developed model effectively identified high-risk NPC patients vulnerable to RTI ≥5 days, with IC shown to mitigate this risk. These findings support the implementation of risk-stratified treatment strategies and proactive IC use to counter unavoidable treatment delays.

Translational OncologyVol. 67
Guangxi Medical University (CN), Guangxi Zhuang Autonomous Region Health and Family Planning (CN), Wuzhou Red Cross Hospital (CN)
Openalex Percentile: Top 23%
Head and Neck Cancer Studies
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