Macrophage Phenotype Alterations in Treated Periodontitis Patients Suggest a Pro‐Inflammatory Bias
In this exploratory study, MDMs from individuals with successfully treated stage III, grade B or C periodontitis exhibited a tendency toward a M1-like phenotype across different polarization conditions, indicating the possible persistence of a pro-inflammatory immune trait that requires confirmation in longitudinal and mechanistic studies.
Authors
- Luciana Saraiva (ORCID: https://orcid.org/0000-0001-7592-7538)
- C. M. Pannuti
- Ana Paula Lepique (ORCID: https://orcid.org/0000-0002-4707-2912)
- Mariane Cristina Sloniak (ORCID: https://orcid.org/0000-0002-1125-4888)
- Josiane Betim de Assis
- Cristina Cunha Villar
Institutions
- Universidade de São Paulo (BR)
- Institute of Biomedical Science (GB)
Publication Details
- Journal
- Journal of Periodontal Research
- Published
- 2026-03-11
- DOI
- https://doi.org/10.1111/jre.70098
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00