Development and Internal Multicenter Validation of a Deep Learning Model for Predicting Post-Hepatectomy Liver Failure in Patients with Hepatocellular Carcinoma: A Multicenter Study

The deep learning model provides improved predictive performance for post-hepatectomy liver failure compared with logistic regression in an internally validated multicenter cohort and may support perioperative risk stratification and surgical planning.

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Publication Details

Journal
Cancers
Published
2026-03-12
DOI
https://doi.org/10.3390/cancers18060926
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
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article

Development and Internal Multicenter Validation of a Deep Learning Model for Predicting Post-Hepatectomy Liver Failure in Patients with Hepatocellular Carcinoma: A Multicenter Study

Xulin Liu, Zhenheng Wu, Jing Ying Yan, Zheng Huang et al.
Cancers
Hepatocellular Carcinoma Treatment and Prognosis
article

Development and Internal Multicenter Validation of a Deep Learning Model for Predicting Post-Hepatectomy Liver Failure in Patients with Hepatocellular Carcinoma: A Multicenter Study

Xulin Liu, Zhenheng Wu, Jing Ying Yan, Zheng Huang, Feng Xia, Zhancheng Qiu, Bin Guo, Qian Chen, Qiao Zhang, Zhicheng Liu, Chang Shu, Xiaoping Chen, Bixiang Zhang, Peng Zhu
article en

Abstract

The deep learning model provides improved predictive performance for post-hepatectomy liver failure compared with logistic regression in an internally validated multicenter cohort and may support perioperative risk stratification and surgical planning.

CancersVol. 18(6)
Fujian Medical University (CN), Sichuan University (CN), West China Hospital of Sichuan University (CN), Zhongshan People's Hospital (CN), Zhongshan Hospital (CN), First Affiliated Hospital of Shihezi University Medical College (CN), Central Hospital of Wuhan (CN), Wuhan General Hospital of Guangzhou (CN), Second Affiliated Hospital of Zhejiang University (CN), Tongji Hospital (CN), Union Hospital (CN), Huazhong University of Science and Technology (CN)
Peace, Justice and strong institutions
Openalex Percentile: Top 28%
Hepatocellular Carcinoma Treatment and Prognosis
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