Signet-ring Cell Pattern in Pancreatic Juice Cytology Indicates Intestinal-type Intraductal Papillary Mucinous Neoplasm with High-grade Dysplasia or Invasive Carcinoma

SRC pattern, defined as the presence of ≥ 30 SRC-like cells in PJC, may be a supportive cytological finding for diagnosing IPMN with HGD/IC, particularly the intestinal subtype. Furthermore, the mucus coloration of SRC-like cells might reflect subtype‑related morphological tendencies.

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Publication Details

Journal
Acta Cytologica
Published
2026-03-12
DOI
https://doi.org/10.1159/000551473
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Signet-ring Cell Pattern in Pancreatic Juice Cytology Indicates Intestinal-type Intraductal Papillary Mucinous Neoplasm with High-grade Dysplasia or Invasive Carcinoma

Yuki Obara, Megumi Orita, Kenichi Hirabayashi, Yui Yoshida et al.
Acta Cytologica
Pancreatic and Hepatic Oncology Research
article

Signet-ring Cell Pattern in Pancreatic Juice Cytology Indicates Intestinal-type Intraductal Papillary Mucinous Neoplasm with High-grade Dysplasia or Invasive Carcinoma

Yuki Obara, Megumi Orita, Kenichi Hirabayashi, Yui Yoshida, Mari Fujioka, Akiko Hashimoto, Kazuto Ikeda, Ayumi Hagiwara, Yosuke Tajika
article en

Abstract

SRC pattern, defined as the presence of ≥ 30 SRC-like cells in PJC, may be a supportive cytological finding for diagnosing IPMN with HGD/IC, particularly the intestinal subtype. Furthermore, the mucus coloration of SRC-like cells might reflect subtype‑related morphological tendencies.

Acta Cytologica
Openalex Percentile: Top 25%
Pancreatic and Hepatic Oncology Research
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