Characterization of near-complete human <i>Pegivirus</i> 2 (HPgV-2) genomes in individuals co-infected with hepatitis C virus (HCV) in Cameroon
Human <i>pegivirus</i> (HPgV) genomes were detected in HCV-infected plasma via nanopore metagenomics. Six nearly complete HPgV-2 genomes were identified. Phylogenetic analysis confirmed HPgV-2 genotype. This study reveals co-infection dynamics, highlights viral diversity, and supports improved diagnostics.
Authors
- Simon Frédéric Lissock
- Janin Nouhin (ORCID: https://orcid.org/0000-0003-4985-8377)
- Jean Paul Assam Assam (ORCID: https://orcid.org/0000-0001-6601-2934)
- Leakhena Pum
- Abdou Fatawou Modiyinji (ORCID: https://orcid.org/0000-0001-6706-3012)
- Pretty Rosereine Mbouyap
- Aristide Mounchili-Njifon
- Moise Henri Moumbeket-Yifomnjou
- Richard Njouom
- Loique Landry E. Messanga
- Vireak Heang
- Ladifatou Nzi Mbouo-Njoya
- Erik A. Karlsson
- Desmon Toutou Toutou Tsafack
Institutions
- Université de Yaoundé I (CM)
- Centre Pasteur du Cameroun (CM)
- Institut Pasteur du Cambodge (KH)
Publication Details
- Journal
- Microbiology Resource Announcements
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1128/mra.00069-26
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00